Aggrephagy

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

本事件系通过计算推理自另一物种中已证实的同类事件得出。推理过程基于PANTHER的同源性映射。简言之，对于所有参与物理实体（包括输入、输出及催化剂）均具有对应同源或旁系同源映射的反应（对于复合体而言，至少75%的组分需具备映射），均推定至其他物种。此外，为便于导航，对这些事件也进行了高级别事件的推定。关于Reactome中事件推理的更多细节及注意事项，请参阅<a href='/electronic_inference_compara.html' target = 'NEW'>详细信息</a>。欲了解更多关于PANTHER的信息，请参见<a href='http://www.pantherdb.org/about.jsp' target='NEW'>PANTHER简介</a>。