Small molecule inhibitor of PRC1 E3 ligase activity induces differentiation of leukemia initiating cells [ChIP-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP173597
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资源简介:
We have developed small molecule inhibitors of PRC1. These inhibitors target PRC1, decrease H2A ubiquitination and differentiation of TEX cells. Overall design: TEX cells treated with DMSO or 25uM WY332 compound for 6 days followed by immunoprecipitation with anti-H2Aub antibody. ChIP sequencing was performed and analyzed by ActiveMotif.
创建时间:
2021-07-07



