Functionally relevant regions of the D-loop.

afunctionally relevant regions of the D-loop adapted from www.mitomap.org[32], bmtDNA position according to rCRS [29], cLSP region alone also indicated at m.392 to m.445 [49], dHSP2 was indicated at www.mitomap.org[32] as m.645 [52]–[54], however, more recent investigation mapped start of HSP2 at m.644 [26], [27]; m.632 to m.655 was selected as HSP2 region, as Lodeiro et al. [27] randomized these 24 nucleotides around the transcription start and did not detect transcription in vitro, thus, these 24 nucleotides might be important HSP2 control elements (e.g. transcription factor binding sites).
CE, control element; CSB, conserved sequence block; ETAS, extended termination associated sequence, HSP, heavy strand promoter; HV, hypervariable region; LSP, light strand promoter; mtTF1 BS, mitochondrial transcription factor A (TFAM) binding side (TFAM, formerly known as mtTF1), OXPHOS, oxidative phosphorylation; TAS, termination associated sequence.