Association of CORIN rs2271036 and rs2271037 single nucleotide polymorphisms (SNPs) with preeclampsia (PE).

Results are given in the discovery (S1), replication (S2) and combined (C) samples, in Caucasian subjects from Europe (Eur), Maghreb (Mgh) or Sub-Saharan-African subjects (Afr).*Genotypes are expressed as percentage (number) of patients with TT/TC/CC genotype for rs2271036 and as TT/TG/GG genotype for rs2271037, respectively.†ORs (95% IC, p values) calculated in a dominant model, adjusted for nulliparity and obesity, associated with the (CC+CT) versus the TT genotype (rs2271036) or with the (GG+GT) versus the TT genotype (rs2271037). MAF, minor allele frequency.‡Significantly different when compared to the control group (chi-square test adjusted for nulliparity and obesity).Association of CORIN rs2271036 and rs2271037 single nucleotide polymorphisms (SNPs) with preeclampsia (PE).