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Longituinal antibody sequences from Rhesus Macaques immunized with germline targeting Q23-APEX-GT2 immunogen

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NIAID Data Ecosystem2026-05-02 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP566716
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资源简介:
This dataset contains demultiplexed longitudinal antibody sequencing data from 12 rhesus macaques (Macaca mulatta) immunized with the V2-Apex germline-targeting Q23-APEX-GT2 immunogen. The study tracks the evolution of B cell receptor (BCR) repertoires over 3 time points post-immunization and 1 time point prior to immunization, providing insights into immune responses and the progression of antibody maturation. These data contribute to understanding the efficacy of V2-Apex germline-targeting strategies in guiding antibody development toward broadly neutralizing epitopes, with implications for HIV-1 vaccine design.
创建时间:
2025-03-01
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