Single-Cell RNA Sequencing Investigation of the Duodenal Mucosa in Canine Chronic Inflammatory Enteropathy and Health

We used single-cell RNA sequencing to characterize the heterogeneity duodenal tissue in healthy and chronic inflammatory enteropathy (CIE) affected dogs. Overall design: The complete dataset consists of 150bp paired end sequencing data obtained using a 10x Genomics single-cell RNA sequencing platform (Chromium Next GEM Single Cell 3' Kit v3.1 protocol). The final dataset consists of data from 7 biologically distinct dogs (3 healthy and 4 diagnosed with CIE).