Effect of 1968/GPFc antibody on maternal mortality and congenital GPCMV infectionAB.

APregnant guinea pigs were infected with 4×103 PFU of IVP8 at the start of the 2nd trimester.BCumulative results at 21 days post-infection.CVirus detected by quantitative PCR.DVirus detected by nested PCR.EAntibody administered I.P. one day prior to infection at 8 mg/kg dose and then twice per week for 3 weeks with a total of six doses (see Figure 5 for study scheme).Fn/a, not applicable, no fetuses were alive at end of study.GAveraged in-house historical data from infected pregnant guinea pigs without antibody treatment.