Fat_challenge_tests

Exploration of new markers that define impaired metabolic flexibility using an acute postprandial challenge test. Healthy subjects underwent a 4-week high-fat high-calorie diet. High-fat challenges were performed in these subjects before and after the diet and in subjects with the metabolic syndrome. Whole blood gene expression was measured from total blood RNA at fasting and at 120 and 360 min after the high-fat challenges.