File S1 - De-Regulated MicroRNAs in Pediatric Cancer Stem Cells Target Pathways Involved in Cell Proliferation, Cell Cycle and Development

Supplemental data. Figure S1, Scatter plots of raw ΔCt of 6 cell lines between test (enriched CSC miRNAs) and reference (non-enriched counterpart) samples before normalization. Figure S2, Heatmap of 865 putative microRNA target genes computed by . 630 of the putative microRNA target genes were up-regulated and 235 were down regulated. The values of 865 target genes were computed by (see Eq. 2 in Methods Section for details). Figure S3, The CSC associated DEmiRs regulated Biocarta pathways. (A–D) CELLCYCLE, G1, P53, and RACCYCD pathways, (E–H) CTCF, TOB1, ALK, and PTEN pathways. Table S1, Cell cycle and cell proliferation related genes in the cancers. (√ indicates the gene is in the gene set named in the column header). (PDF)