TNF blockade uncouples toxicity and anti-tumor efficacy induced with an agonist CD40 antibody
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE156160
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资源简介：
TNF mechanistically links cytokine release and hepatotoxicity triggered by an agonist CD40 antibody, and toxicity can be suppressed by blockade of TNF without affecting anti-tumor efficacy. mRNA sequencing of bulk liver tissue collected from wild-type mice at 48 hours after treatment with the CD40 agonist FGK45 (compared to control)
创建时间：
2021-09-08
