Samarium(III)-Catalyzed C(sp3)–H Bond Activation: Synthesis of Indolizines via C–C and C–N Coupling between 2‑Alkylazaarenes and Propargylic Alcohols

A new rare earth metal and samarium-catalyzed C­(sp3)–H bond activation is reported in which 2-alkylazaarenes and propargylic alcohols were converted to indolizines. This process operates under mild conditions and solvent-free conditions. A broad scope of coupling partners has been established, and a likely mechanism has also been suggested.