FAIRsharing record for: Clinical and Registry Entries Semantic Model

This FAIRsharing record describes: Clinical And Registry Entries (CARE-SM) is a semantic data model designed to effectively represent healthcare patient information by using knowledge graphs represented in the Resource Description Framework (RDF). This technical description aims to provide a comprehensive overview of CARE-SM, its origins, and the design principles that underlie its structure.

CARE-SM is built upon the Semanticscience Integrated Ontology (SIO) as its core structural schema. SIO is used to define every concept within the data model, utilizing upper-class classes and properties. This knowledge graph serves as an "scaffold" that hold every data element within its structure Figure 1. By a combination of these instances defined by SIO, it becomes possible to represent every clinical entry comprehensively.

Moreover, each instance within CARE-SM is associated with a domain-specific ontological class from the OBO Foundry. For instance, the representation of patient birthdate is described at a upper-class level using the ontological term SIO:attribute and, at a domain-specific level, as NCIT:Birthdate. This dual ontological characterization enhances data interoperability and precise semantic descriptions.