Total Synthesis of Azumamide E and Sugar Amino Acid-Containing Analogue
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An efficient and practical total synthesis of marine cyclic tetrapeptide, natural product azumamide E (1) is achieved via high-yielding reactions. The strategy also allowed us to synthesize the azumamide E-SAA (sugar amino acid) analogue (2), whose solution-phase NMR and biological activity studies were also carried out.
创建时间:
2009-01-02



