High-IgG titer group includes subjects whose titers against Porphyromonas gingivalis (PgFDC381 and/or PgSu63) are above mean+2SD of healthy subsets [20]. “Frequent exacerbations” are defined as ≥2 exa
Calculated cut-off median fluorescence intensity (MFI) values for the different Streptobacillus species based on mean values of the negative sample set + three standard deviations.
(A) After fixing with 4% paraformaldehyde and blocking with goat serum, M2 type macrophage cells were incubated with C1q, C1q plus rTs-Pmy or PBS alone for 1 h at 37°C, and then detected with an anti-