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Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia

ChEBI2016-06-29 更新2026-07-12 收录

急性髓系白血病

MLL重排肿瘤

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68463 数据链接链接失效反馈

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Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia

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创建时间：

2016-06-29

急性髓系白血病

耐药性机制

Targeting the MYST acetyltransferases are an exciting therapeutic opportunity in acute myeloid leukaemia (AML). Here we define the individual and combined contribution of KAT6A, KAT6B and KAT7, in ran

NIAID Data Ecosystem90

CARM1/PRMT4 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis

急性髓系白血病

RNA-seq转录组学

We investigated the role of PRMT4 in normal and malignant hematopoiesis. We found that knockdown of PRMT4 impairs cell cycle progression, induces apoptosis, and downgretulateds E2F target genes in leu

NIAID Data Ecosystem50

Supplementary Table 2 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

急性髓系白血病

转录因子调控

Transcription Factor Enrichment Analysis of MOLM13 Bulk RNA-Seq (24 Hours After Drug Treatment)

Figshare2023-07-05 更新40

RNA sequencing expression analysis of murine MLL-AF9;NRAS acute myeloid leukemia cells silenced for E2-2.

急性髓系白血病

RNA测序

We investigated the role of the transcriptional regulators Id2 and E2-2 (encoded by Tcf4) in the context of MLL-rearranged acute myeloid leukemia (AML). Using an AML mouse model driven by a Tet-off in

干细胞与再生医学数据中心2022-02-20 更新80

Kynurenine engages Serotonin Receptor 1b in osteoblasts to reinforce Acute Myeloid Leukemia

急性髓系白血病

白血病研究

We performed RNAseq analysis of primary human osteoblasts co-cultured with the human THP-1 AML cell-line and, in parallel, RNAseq analysis on the THP-1 AML cells exposed to the human primary osteoblas

NIAID Data Ecosystem40

Id2 and E proteins orchestrate the initiation and maintenance of MLL-rearranged acute myeloid leukemia

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