Appendix III: Crossover activity

PhD thesis: PRDM9 Diversity, Recombination Landscapes and Childhood Leukaemia by Ihthisham Ali <br><br>Appendix III contains hotspot activity analysis data on DNA3 and AA hotspots in a MHCII sub-region. These data is indicative of the local recombination profile in the MHCII and provides confirmatory evidence for the differential activation of PRDM9 A and a subset of Ct alleles for these two hotspots. Additionally, these data provide fine-scale information on the morphology of the AA hotspot.<br>A. DNA3 hotspot CO activity dataB. DNA3 hotspot Chi-Squared TestC. AA hotspot CO activity dataD. AA hotspot d257 (20) breakpoint mappingE. AA hotspot d257 (20) hotspot morphology graph data