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Tcf1-CTCF cooperativity shapes genomic architecture to promote CD8+ T cell homeostasis [CTCF Cut&Run]

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP327485
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资源简介:
An intricate interplay among Tcf1/Lef1, CTCF and Stat5 that orchestrates genomic architecture to coordinately promote CD8+ T cell homeostatic proliferation Overall design: Splenocytes were harvested from hCD2-Cre, Rosa26-lsl-GFP, Tcf1/Lef1 wild-type or double floxed mice, and sorted for GFP+TCRbeta+ naïve CD8+ T cells. The sorted cells were stimulated with IL-7 and IL-15 for 0 or 72 hrs, and the live cells wer used for CTCF Cut&Run.
创建时间:
2023-04-04
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