Benchmark WGBS data (sample 4 in 2 versus 2 sample comparison)
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Benchmark WGBS data (sample 4 in 2 versus 2 sample comparison)This file contains simulated benchmark WGBS data for 1 sample from a 2 vs 2 comparison saved as a `.txt.gz` (compressed text file). The tab-delimited text file contains four columns: chromosome, position, number of methylated reads, and total number of reads coverage.This benchmark data was created to mimic the properties of real WGBS data in order to evaluate the method dmrseq (described in the preprint at https://doi.org/10.1101/183210). This was done by splitting a set of biological replicates (controls) into two artificial groups and adding methylation differences to randomly selected regions. Differences are added between the first half of samples and the second half of samples. More methodological details and a script to reproduce the generation of this data file is available at the companion repository: https://github.com/kdkorthauer/dmrseqPaper.
创建时间:
2017-12-12



