MSMO1
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Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
基于其与酵母ERG25蛋白的相似性,分离得到了一种类固醇-C4-甲基氧化酶蛋白。该蛋白含有一系列假定的金属结合基序,与膜脱饱和酶-羟化酶家族中观察到的相似。该蛋白定位于内质网膜,并认为其在胆固醇生物合成中发挥作用。针对该基因,已发现编码不同亚型的选择性剪接转录变体。[由RefSeq提供,2008年7月]
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