Crystal structure of BRD2(BD2)with ligand BY27 bound
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Crystal structure of BRD2(BD2)with ligand BY27 bound Descriptor: (6~{R})-~{N}-(4-chlorophenyl)-1-methyl-8-(1-methylpyrazol-4-yl)-5,6-dihydro-4~{H}-[1,2,4]triazolo[4,3-a][1]benzazepin-6-amine, Bromodomain-containing protein 2 Authors: Lu, T, Lu, W, Chen, D, Zhao, Y, Luo, C. Deposit date: 2019-05-05 Release date: 2019-09-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.251 Å) Cite: Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins. Eur.J.Med.Chem., 182, 2019
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2019-05-05
