The PODER cross-ancestry long-read RNA-seq dataset

Table legends:

column_descriptions.docx: Extended description of columns in selected tables.

00_sample_metadata: Sample and experimental metadata pertaining to each LR-RNA-seq sample.

01_uma_gtf: Unfiltered merged annotation (UMA) GTF for all spliced intron chains discovered by each of the tools.

02_uma_mt: Metadata table for SQANTI QC, Recount3 support, protein prediction, and other relevant characteristics for each transcript in the UMA annotation used to filter transcripts.

03_poder_gtf: Final PODER GTF, including predicted CDSs for novel transcripts and annotated CDSs for known transcripts.

04_poder_mt: Metadata table for SQANTI QC, Recount3 support, protein prediction, and other relevant characteristics for each transcript in PODER.

06_poder_t_counts: PODER transcript counts in each sample as quantified by lr-kallisto.

07_poder_g_counts: PODER gene counts in each sample as quantified by lr-kallisto.

08_mage_t_counts_poder: Transcript counts for the MAGE RNA-seq dataset computed using the PODER annotation with kallisto.

09_mage_t_counts_gencode: Transcript counts for the MAGE RNA-seq dataset computed using the GENCODE annotation with kallisto.

10_mage_t_counts_enh: Transcript counts for the MAGE RNA-seq dataset computed using the Enhanced GENCODE annotation with kallisto.

11_astu: Allele-specific transcript usage results.

12_ase: Allele-specific expression results.

13_mage_tau: Tau values for Enhanced GENCODE transcripts computed on the MAGE RNA-seq dataset.

14_gwas_enrichments: GWAS enrichment results for ASTU genes overlapping GWAS genes.

16_inter_catalog_overlap: Boolean detection of transcripts across PODER, annotations (GENCODE, RefSeq) and other RNA-seq / LR-RNA-seq-derived transcript catalogs (CHESS, GTEx, ENCODE4).

17_personalized_hg38: Isoforms and their intron chains detected using personalized-GRCh38s.

18_enh_gencode: Enhanced GENCODE GTF with novel transcripts from PODER added to all annotated transcripts from GENCODE v47