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Crystal Structure of the human mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgADP

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal Structure of the human mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgADP Descriptor: 5-acetyl-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... Authors: Dougan, D.R, Mol, C.D. Deposit date: 2010-03-25 Release date: 2010-07-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2010-03-25
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