Pentavalent vanadium compounds induce intracellular changes in vitro that are consistent with those of other carcinogenic substances, including alteration of transcription factor levels, promotion of
The requirements of amended Toxic Substances Control Act (TSCA) stipulates that the US Environmental Protection Agency (US EPA) evaluate existing chemicals and make risk based assessments. There are ~
Farm workers are at an increased risk for the development of acute and chronic lung inflammatory diseases from their everyday exposures to organic dust. Previous investigations have examined the infla
This dataset was generated in an in vivo systems toxicology study where Apoe-/- mice were exposed to cigarette smoke or aerosols of two different heat-not-burn platforms, THS 2.2 and CHTP 1.2, for up
Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2. Characterization of the nasal e
