Detect the difference of m6A modification in different stage oocyte of Xenopus laevis, and the functions of mRNA m6A modification during oocyte maturation and early embryo development.
N6-methyladenosine (m6A) plays diverse roles in the regulation of mRNA metabolism. In the mammalian brain it has been linked to developmental processes, memory function and plasticity. However, the pr
Epitranscriptome is an exciting area that studies different types of modifications in transcripts, and the prediction of such modification sites from the transcript sequence is of significant interest
N6-methyladenosine (m6A) is an abundant RNA modification in eukaryotes, playing crucial roles in multiple biological processes. m6A is catalyzed by the activity of Mettl3, which depends on additional