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TNF-R1 Co-opts TLR4 Pathway Components CD14, TRAM and TRIF to Drive TNF-Induced Inflammation and Toxicity

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE211539
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We report the application of single-cell-sequencing technology for the profiling of TRIF-dependent changes in immune cell populations, and TRIF-dependent cellular responses in the spleens of mice 4 hours after intravenous injection with recombinant murine TNF. Examination of the effect of TRIF-deficiency on cellular responses in the spleens of TNF-injected mice
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2022-08-23
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