Figure S2 - Lifetime-Dependent Effects of Bisphenol A on Asthma Development in an Experimental Mouse Model

BPA exposure during OVA-sensitization reduced allergic airway inflammation in a dose-dependent manner. Adult mice were exposed to BPA via drinking water during OVA-immunisation protocol. BPA exposure reduced total cell number in BAL fluid (a), OVA-specific IgE serum levels (b) and lung resistance (c). Cytokine production from CD4+ lung T cells was not affected (d). Data are expressed as mean ± SEM, n≥7 animals per group. *P<0.05, **P<0.01 of OVA +5 µg/ml BPA and #P<0.05 of OVA +25 µg/ml BPA compared to OVA.
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