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Improving Foldamer Synthesis through Protecting Group Induced Unfolding of Aromatic Oligoamides

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Improving_Foldamer_Synthesis_through_Protecting_Group_Induced_Unfolding_of_Aromatic_Oligoamides/3051868
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The hydrogen bond rigidified backbones of aromatic oligoamides are temporarily interrupted by replacing the amide hydrogens with the acid-labile 2,4-dimethoxybenzyl (DMB) group, which allows the efficient preparation of long folding oligomers that, upon removal of the DMB groups, fold into multiturn helices.
创建时间:
2006-10-26
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