Intestinal stem cell differentiation is associated with dynamic changes in the chromatin landscape
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2019-05-24
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Transcriptional regulators compete with nucleosomes post-replication. Drosophila melanogaster
Every nucleosome across the genome must be disrupted and reformed when the replication fork passes, but how chromatin organization is re-established following replication is unknown. To address this p
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Identification of differentially-expressed miRNA, piRNA and circRNA in early osteogenic and chondrogenic differentiation of human bone marrow-mesenchymal stromal cells (hMSCs)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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Table_4_Evidence That Ion-Based Signaling Initiating at the Cell Surface Can Potentially Influence Chromatin Dynamics and Chromatin-Bound Proteins in the Nucleus.xlsx
We have developed tools and performed pilot experiments to test the hypothesis that an intracellular ion-based signaling pathway, provoked by an extracellular stimulus acting at the cell surface, can
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Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for histone H2A variants and histone modifications in WT Col-0 seedlings.. Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for histone H2A variants and histone modifications in WT Col-0 seedlings.
How histone intrinsic sequence variation or regulatory modifications regulate nucleosome interactions with transcription remain unclear. To clarify this question, we examined how histone variants and
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Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis [mg633_ATACseq]. Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis [mg633_ATACseq]
ATAC-seq was performed on MG63.3-GFP cells in vitro or isolated from mouse lung 1 day or 22 days post-innoculation to assess chromatin accessbility dynamics during lung colonization. Overall design: C
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