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Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21b

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6tg1
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资源简介:
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21b Descriptor: 1,2-ETHANEDIOL, Epidermal growth factor receptor, SODIUM ION, ... Authors: Niggenaber, J, Mueller, M.P, Rauh, D. Deposit date: 2019-11-14 Release date: 2020-09-30 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. J.Med.Chem., 63, 2020
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2019-11-14
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