Human TNF-alpha TNFR1 complex bound to conformationally selective antibody
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Human TNF-alpha TNFR1 complex bound to conformationally selective antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one, Fab1974 - Heavy Chain, ... Authors: Fox III, D, Conrady, D.G, Lowe, M, Ceska, T. Deposit date: 2020-11-10 Release date: 2021-01-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3 Å) Cite: A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF Nat Commun, 12, 2021
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2020-11-10
