Data for: Network of autoscopic hallucinations elicited by intracerebral stimulations of periventricular nodular heterotopia: an SEEG study

Periventricular nodular heterotopias (PVNH) are areas of neurons
abnormally located in the white matter that might be involved in
 physiological cortical functions. Autoscopic hallucinations are
changes in self-consciousness determined by a mismatch in integration of
multiple sensory inputs. Our goal is to highlight the brain network
involved in generation of autoscopic hallucination elicited by electrical
stimulation of a PVNH in a drug resistant epilepsy patient.  Our
patient was explored using stereo-electroencephalography with electrodes
covering the right posterior temporal PVNH and the adjacent cortex. Direct
electrical high frequency stimulation of the PVNH elicited autoscopic
hallucinations mainly involving the face and upper trunk. We then used
multiple modalities to determine brain connectivity: single pulse
electrical stimulation of the PVNH and stimulation-evoked potentials were
used to highlight resting state effective connectivity. High-frequency
stimulation using alternating polarity pulses enabled us to identify the
network involved, time-locked to the clinical effect and to map
symptom-related effective connectivity. Functional connectivity using a
non-linear regression method was used to determine dependencies between
different cortical regions following the stimulation. Finally, structural
connectivity was highlighted using deterministic fiber tracking.
Multi-modal connectivity analysis identified a network involving the PVNH,
occipital and temporal neocortex, fusiform gyrus and parietal cortex.