Hnf4 controls gut and liver gene programs in the thymus [bulk_RNAseq]

Alliance of Genome Resources2026-08-01 收录

T细胞耐受

上皮细胞转录组

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http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=GSE225659 数据链接链接失效反馈

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We profiled medullary thymic epithelial cells by bulk RNA-seq to investigate mechanisms of T-cell tolerance. Bulk RNA-seq of mTECs

Microarray analysis of RNA of TCR transgenic CD8 T cells to assess the role of protein glycosylation in the decision between deletion vs. anergy in immune tolerance

T细胞耐受

糖基化调控

Activation of peripheral T lymphocytes in the absence of pathogen induced inflammation or costimulatory signals results in tolerance. Two different tolerance mechanisms have been described, deletion a

NIAID Data Ecosystem40

RNA-seq analysis on mTECs from Fezf2KO, AireKO and Chd4cKO mice

上皮细胞转录组

免疫耐受调节

To gain insights into the difference in transcriptional programs regulated by Fezf2, Aire and Chd4, we performed RNA sequencing (RNA-seq) of mTECs from Fezf2-deficient, Aire-deficient and Chd4-deficie

NIAID Data Ecosystem20

Transcriptome analysis of cultured human alveolar epithelial type 2 cells. Transcriptome analysis of cultured human alveolar epithelial type 2 cells

上皮细胞转录组

基因转导效应

We investigated whether in vitro expansion of human alveolar epithelial type II cells is possible. We found that human endogenous human alveolar epithelial type II cells can be cultured and passaged.

NIAID Data Ecosystem10

RNAseq of tolerized auroreactive RBC-specific CD4 T cells, HODxOTII murine model of autoimmune hemolytic anemia (AIHA)

自身免疫性溶血性贫血

T细胞耐受

We have previously identified that T cell tolerance is the stopgap to red blood cell (RBC)-specific autoimmunity. We have also shown that while tolerance is robust when mice are young, it fails upon a

DataONE2024-07-24 更新40

Comparison of the transcriptome analysis of Tom[Low] and Tom[High] AT2 subpopulations in mice. Comparison of the transcriptome analysis of Tom[Low] and Tom[High] AT2 subpopulations in mice

上皮细胞转录组

Fgfr2b信号通路分析

Transgenic mice in two control (SftpCreERT2/+; Tomatoflox/flox) and Experimental (SftpCreERT2/+; Fgfr2bflox/flox; Tomatoflox/flox) groups were treated with tamoxifen (1mg/ml) in drinking water. The lu

NIAID Data Ecosystem20

Hnf4 controls gut and liver gene programs in the thymus [bulk_RNAseq]

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