A multi-omics molecular landscape of 30 tissues in aging female rhesus macaques (Macaca mulatta)

We generated and analyzed multi-omics data, including transcriptome, proteome, and metabolome, from 30 tissues of 17 female rhesus macaques (Macaca mulatta) aged 3 to 27 years.

The omics data are freely and publicly available. Level-2 data, including transcriptome raw counts and log2 peak areas for the proteome and metabolome, are accessible on this Figshare.

The code to reproduce the results in this study is available at this Figshare or GitHub: https://github.com/GonghuaLi/Macaca_30tissue_aging. Supplementary Data 10 provides a comprehensive PDF document generated from the coding of R Markdown (RMD) file, containing all code and results.

For the level-1 raw data, the raw FASTQ files of the transcriptome have been deposited in the Genome Sequence Archive at the National Genomics Data Center (GSA: CRA026248), publicly accessible at https://ngdc.cncb.ac.cn/gsa. The raw LC-MS/MS data for the proteome have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD066108 and also deposited to OMIX (https://ngdc.cncb.ac.cn/omix, accession no. OMIX001778). The raw LC-MS/MS data for the metabolome are deposited in OMIX (https://ngdc.cncb.ac.cn/omix, accession no. OMIX001779).