Simulation results of the nine-species community model (bilinear and linearized full model and reduced model).

The minimum and maximum substrate uptake and product formation rates were computed with nonlinear optimization (bilinear model), FVA (linearized full model) or EFV analysis (reduced model). The community growth rate was set to 0.00067 h-1 (linearized full model, reduced model), which was the dilution rate used in an experiment with an enrichment culture grown on glucose-cellulose medium. The experimental data of two experiments and their average is also listed in the table. The nine species in the model are: E. coli, C. acetobutylicum, S. wolfei, P. freudenreichii, A. wooddii, D. vulgaris, S. fumaroxidans, M. barkeri and M. hungatei (see also Tables 1 and 2).