Combined Probiotics and Phenolics Reshape the Gut Microbiome

Western dietary patterns are a major driver of cardiometabolic dysfunction, partly mediated by gut microbiota dysbiosis and sustained inflammation along the gut brain axis. In this study, we investigated whether a synbiotic formulation combining Limosilactobacillus fermentum strains with the polyphenols, quercetin and resveratrol could mitigate cardiovascular, gut microbiota and neuroinflammatory alterations induced by a Western diet.