The surface roughness parameters Ra and Rq as a function of the paclitaxel treatment time in Ishikawa and HeLa cells.

The roughness was analyzed in two randomly selected small areas of 6×6 µm2 and 3×3 µm2 to avoid any artifact caused by the cell structure. P value corresponds to the statistical results between the control (0 h) and the paclitaxel treated cells (6 h–48 h).P-value is the statistical result between the nontreated cell and taxol treated cell.