Spheroid growth assays as a function of glutamine, pyruvate, biotin and FBXW7.
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We hypothesized that 293T spheroids could model proliferation as a result of nutrient (glutamine, pyruvate, biotin) and genetic (FBXW7 KO) perturbation. Our data shows that in the absence of glutamine, pyruvate rescues proliferation only upon biotin supplementation and FBXW7 expression.
创建时间:
2026-01-30



