Crystal structure of PIM1 in complex with a Pyrrolo(1,2-a)Pyrazinone inhibitor
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of PIM1 in complex with a Pyrrolo(1,2-a)Pyrazinone inhibitor Descriptor: N-(2,2-dimethylpropyl)-2-[1-oxo-7-(thiophen-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide, SERINE/THREONINE-PROTEIN KINASE PIM-1 Authors: Casale, E, Casuscelli, F, Ardini, E, Avanzi, N, Cervi, G, D'Anello, M, Donati, D, Faiardi, D, Ferguson, R.D, Fogliatto, G, Galvani, A, Marsiglio, A, Mirizzi, D.G, Montemartini, M, Orrenius, C, Papeo, G, Piutti, C, Salom, B, Felder, E.R. Deposit date: 2013-07-29 Release date: 2013-10-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery and Optimization of Pyrrolo[1,2-A]Pyrazinones Leads to Novel and Selective Inhibitors of Pim Kinases. Bioorg.Med.Chem., 21, 2013
创建时间：
2013-07-29
