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Aryl hydrocarbon receptor-dependent and -independent pathways mediate curcumin anti-aging effects

Alliance of Genome Resources2026-08-01 收录

抗衰老药理学

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https://www.wormbase.org/resources/analysis/Microarray_Study.WBPaper00064073.ce.mr 数据链接链接失效反馈

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In this study we investigated if curcumin has AhR-dependent effects on aging. This transcriptomic analysis should help shed light on the AhR-dependent and AhR-independent mechanisms of curcumin.

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前列腺癌分子机制

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Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation. We identified RUNX1 is an androgen-regulated gene. In order to investigate the

NIAID Data Ecosystem30

A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [ChIP-seq]

乳腺癌分子机制

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Estrogen and estrogen receptor alpha (ERα) signaling plays an essential role in ERα-positive breast cancer. ERα mainly occupies on distal enhancers within genome and requires the cooperation of additi

NIAID Data Ecosystem20

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

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Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem10

Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation. Homo sapiens

RNA稳定性调控

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Roquin2, and its paralog Roquin1, are key regulator of mRNA decay. Roquin proteins recognize mRNAs containing a 3’-UTR stem-loop motif, called constitutive decay element (CDE), through the ROQ domain.

NIAID Data Ecosystem20

DataSheet_1_Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity TCRB and TCR Signaling Pathways.pdf

类风湿关节炎滑膜病理

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ObjectivesWe explored histological and transcriptomic profiles of paired synovial biopsies from rheumatoid arthritis (RA) patients, in order to assess homogeneity in synovial tissue at the individual

NIAID Data Ecosystem10

Aryl hydrocarbon receptor-dependent and -independent pathways mediate curcumin anti-aging effects

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