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Structure and Absolute Configuration of Fumiquinazoline L, an Alkaloid from a Gorgonian-Derived <i>Scopulariopsis</i> sp. Fungus

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NIAID Data Ecosystem2026-03-07 收录
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Fumiquinazoline L (1), an alkaloid with a heptacyclic skeleton formed via a bridging hemiaminal linkage, was isolated from a gorgonian-derived Scopulariopsis sp. fungus. The structure and absolute configuration of the new compound were identified by comprehensive spectroscopic data and X-ray diffraction analysis. During acid hydrolysis of 1, the isomerization of the valine residue was observed and also studied in different conditions. Fumiquinazoline L (1) showed no cytotoxic or antibacterial activities.

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2016-02-19
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