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Human AKR1B10 mutant V301L complexed with NADP+ and fidarestat

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4gab
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Human AKR1B10 mutant V301L complexed with NADP+ and fidarestat Descriptor: (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldo-keto reductase family 1 member B10, CHLORIDE ION, ... Authors: Cousido-Siah, A, Ruiz Figueras, F.X, Mitschler, A, Podjarny, A. Deposit date: 2012-07-25 Release date: 2013-03-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5971 Å) Cite: X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity. Chem.Biol.Interact, 202, 2013
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2012-07-25
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