Rfx4
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Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including cilium assembly; negative regulation of smoothened signaling pathway; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including central nervous system; eye; future brain; genitourinary system; and liver. Orthologous to human RFX4 (regulatory factor X4). [provided by Alliance of Genome Resources, Nov 2024]
预测可激活 DNA 结合并参与转录激活活性，针对 RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调控区序列特异的 DNA 结合力。在多个过程的上游或其中发挥作用，包括纤毛组装；对 smoothened 信号通路的负向调控；以及对基因表达的调控。位于细胞核内。在多个结构中表达，包括中枢神经系统；眼睛；未来大脑；泌尿生殖系统；以及肝脏。与人类 RFX4（调控因子 X4）同源。[由基因组资源联盟提供，2024年11月]
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