Test No. 248: Xenopus Eleutheroembryonic Thyroid Assay (XETA)

Organisation for Economic Co-operation and Development2026-02-07 收录

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The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of thyroid hormone available for transcription. The test is based on the use of a transgenic frog...