Neutrophilic granule protein promotes lipopolysaccharide-induced iNOS and NO expression in macrophages

Neutrophilic granule protein was identified as a granular protein in neutrophils, but its function in macrophages has not been fully understood. The evidence of this study suggests that NGP plays a crucial role in regulating NO production and promoting bacterial clearance in macrophages, making it a promising target for the prevention and treatment of infectious diseases.