RNA sequencing of secondary heart field- and cardiac neural crest-derived cells from murine aortas

To better understand the role of lineage in smooth muscle cell heterogenity along the length of the aorta, we performed bulk RNA-sequencing transcriptomic analysis on secondary heart field (SHF)-derived and cardiac neural crest derived (CNC)-derived sorted cells from murine aortas. Overall design: Comparison of the transcriptome of SHF-derived (n=3) and CNC-derived (n=3) cells in murine aortas.