Nppc

ENCODES a protein that exhibits hormone activity; hormone receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cGMP-mediated signaling; negative regulation of cell population proliferation; negative regulation of collagen biosynthetic process; PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH decreased body length; decreased body weight; decreased cranium length; ASSOCIATED WITH aortic valve stenosis; heart disease; Hypoxia; FOUND IN extracellular space; secretory granule; protein-containing complex (ortholog); INTERACTS WITH 3',5'-cyclic GMP; 6-propyl-2-thiouracil; acrylamide

编码一种具有激素活性的蛋白质；激素受体结合（同源）；信号受体结合（同源）；参与cGMP介导的信号传导；细胞群体增殖的负调控；胶原蛋白生物合成过程的负调控；参与C型利钠肽信号通路；与身体长度降低、体重降低、颅骨长度降低相关；与主动脉瓣狭窄、心脏病、缺氧相关；存在于细胞外空间；分泌颗粒；含蛋白质的复合物（同源）；与3',5'-环状GMP、6-丙基-2-硫尿嘧啶、丙烯酰胺相互作用。