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Preparation of 3‑Acyl-4-arylcoumarins via Metal-Free Tandem Oxidative Acylation/Cyclization between Alkynoates with Aldehydes

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NIAID Data Ecosystem2026-03-06 收录
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A new and efficient metal-free tandem acylation/cyclization of alkynoates with aldehydes was developed for the synthesis of 3-acyl-4-arylcoumarins. The reaction was achieved by the addition of acyl radical to alkynes and a C–H bond functionalization to form two new C–C bonds simultaneously.

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2016-02-16
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