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Targeting resistance to Smoothened antagonists by inhibiting the PI3K pathway

ChEBI2010-09-29 更新2026-07-21 收录

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PI3K信号通路抑制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-19657 数据链接链接失效反馈

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资源简介：

Targeting resistance to Smoothened antagonists by inhibiting the PI3K pathway

应用场景：

创建时间：

2010-09-29

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转录抑制联合疗法

Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types

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Cholesterol Regulates the Tumor Adaptive Resistance to MAPK Pathway Inhibition

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胆固醇代谢调控

Although targeted MAPK pathway inhibition has achieved remarkable patient responses in many cancers, the development of resistance has remained a critical challenge. Adaptive tumor response underlies

Figshare2021-12-03 更新40

Co-delivery of free vancomycin and transcription factor decoy-nanostructured lipid carriers can enhance inhibition of methicillin resistant Staphylococcus aureus (MRSA)

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纳米药物递送

Bacterial resistance to antibiotics is widely regarded as a major public health concern with last resort MRSA treatments like vancomycin now encountering resistant strains. TFDs (Transcription Factor

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EGFR-TKI resistance

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EGFR-TKI机制研究

EGFR-TKI耐药相关研究的图片与表格

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Supplementary Data from Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance

IDH突变肿瘤耐药

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Supplementary Data from Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance

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