CEBP-ß and PLK1 as Potential Mediators of the Breast Cancer/Obesity Crosstalk: 'in vitro' and 'in silico' approaches inside a spiderweb interaction network

Here, we report a transcriptomics analysis on MCF-7 breast cancer cells exposed to adipocyte conditioned medium (CM) and focus on the functional relevance that CM-affected pathways and processes and related biomarkers may have in breast cancer response to obesity. Overall design: Comparative transcriptomic profile between MCF-7 cells untreated or treated with conditioned medium derived from 3T3L1 mature adipocytes.