The transcriptome of Legionella pneumophila-infected human monocyte-derived macrophages
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE61535
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资源简介：
Analysis of the human monocyte-derived macrophage (hMDM) transcriptional response to L. pneumophila infection at 8 hours post-infection We used microarrays to probe the hMDM transcriptional response to wild type L. pneumophila AA100 infection and its isogenic ankB and T2SS mutants. We identified up-regulation of innate immunity pathways and down-regulation of protein translation pathways hMDMs were isolated from healthy donors and infected with L. pneumophila AA100 and its isogenic ankB and T2SS mutants for 8 h prior to isolation of total RNA and hybridization to Affymetrix microarrays.
创建时间：
2018-07-26
